Font Awesome Icons

In Vıtro Analysıs Of Antı-Fungal Actıvıty And Mechanical Properties of Soft Primer Material Added to Natural Product Extracts

by Fırat Mehmet Günkan | Jan 11, 2022
Within the scope of the study, minimum inhibition concentration and minimum fungicidal concentration (MFC) of propolis and mahaleb extracts were determined by microdilution method using 96-well microplates. Candida albicans ATCC 10231 standard strain was used in the study. Chlorhexidine (0.2%) was preferred as the control group. According to the data obtained from the minimum inhibition concentration experiment, it was determined that propolis extracts were fungicidal and mahalep extracts were fungistatic. In the light of this information, within the scope of the project, propolis was added to the silicone-based soft lining material with the aim of providing antimicrobial property by providing encapsulation of plant or plant origin natural product extracts such as Allium sativum (garlic), Cerasus mahaleb (mahlep), Thymus vulgaris (thyme) by spray drying. With these new additives, the strength tests of the prosthetic material were successfully carried out.

Experimental studies of the Ph.D. Thesis of Istanbul University Faculty of Dentistry, supported by the TUBITAK 1002 Project, were carried out in the Biomechanics and Strength of Materials  laboratory of the ITU Faculty of Mechanical Engineering.

Within the scope of the study, minimum inhibition concentration and minimum fungicidal concentration (MFC) of propolis and mahaleb extracts were determined by microdilution method using 96-well microplates. Candida albicans ATCC 10231 standard strain was used in the study. Chlorhexidine (0.2%) was preferred as the control group. According to the data obtained from the minimum inhibition concentration experiment, it was determined that propolis extracts were fungicidal and mahalep extracts were fungistatic. In the light of this information, within the scope of the project, propolis was added to the silicone-based soft lining material with the aim of providing antimicrobial property by providing encapsulation of plant or plant origin natural product extracts such as Allium sativum (garlic), Cerasus mahaleb (mahlep), Thymus vulgaris (thyme) by spray drying. With these new additives, the strength tests of the prosthetic material were successfully carried out.

03
HTML Image as link

ITU Faculty of Mechanical Engineering

mkn-hakkimizda

ITU Faculty of Mechanical Engineering takes pride in having close to 100 years of Mechanical Engineering tradition, and has currently 33 Professors, 12 Associate Professors, 24 Assistant Professors and 15 Lecturers as Faculty members. At present, we have over 2000 undergraduate students, all of which were selected among the top ~0.5% of the ~2.3 million students taking the nationwide university entrance exam annually.

Founded in 1933, the Faculty of Mechanical Engineering received its current name in 1944. With the university reform in 1933, the Institute of Electricity and Machines of the Istanbul University was replaced by the Electro-Mechanic Department; and by doing so our Mechanical Engineering education, which still continues, began 87 years ago. 11 years later in 1944, the name of the institution was changed to Istanbul Technical University and under it a separate school/college of Mechanical Engineering was founded with the current name: “Faculty of Mechanical Engineering“.

Our faculty is one of the oldest institutions in our country that carries out education and research activities in the field of mechanical engineering. The different engineering branches it hosts have developed and become a faculty. in 1969; Faculty of Naval Architecture and Marine Sciences, in 1983; The Faculty of Textile Technologies and Design and the Faculty of Aeronautics and Astronautics gained their independent status.In the first years, the Mining Engineering department, which was part of the basic sciences and general engineering courses instruct within the scope of the Faculty of Mechanical Engineering, became an independent faculty in 1953.

ITU Faculty of Mechanical Engineering performs research and education in the design, development and production planning of all types of mechanical and energy transformation systems. Our 75 Faculty members are performing research and development in a wide range of areas related to both immediate needs of the industry and also cutting edge science for future technologies and applications. Our research areas include, but not limited to, Automotive Industry, Petrochemical Industry, Robotics, Textile Industry, Defense Industry, Reverse Engineering, Clean Energy, Renewable Energy, Underground Gasification, MEMS, Nanotechnology, Pharmaceutics, and Biomolecular Engineering.

With its gorgeous Ottoman era building providing extensive lab space, massive laboratory and research investment performed in the past 87 years, and the recent addition of the 1500 m2 big Dr. Keskin Keser student lab building, the Faculty of Mechanical Engineering has one of the most extensive educational and research laboratories in Turkey and provides its students with top quality Mechanical Engineering education in a gorgeous historical building located at a prime location in the very heart of Istanbul.